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XVII International Federation
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 QS at HEALTH CONFERENCES AND PROFESSIONAL MEETINGS  AROUND THE WORLD ISSUES AND ANSWERS QS Consent Form Now Available on the web in English as a 79Kb PDF file or in Spanish 71Kb PDF file Note on Pdf's or Download a Microsoft Word file in English in Spanish Instructional Manual Now Available on the Web as html or in English as a 340Kb PDF file in Spanish 341Kb PDF file Note on Pdf's |
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Results of clinical research reported in this issue are reassuring: the method is safe, effective and simple enough to be provided in a basic clinic setting in resource poor areas of the world. In his Forward, Guest Editor, Jack Lippes, summarizes the findings. In addition to the supplement, FIGO dedicated a Session to
the topic "The Future of Quinacrine Sterilization" on Tuesday, November 4, 2003 from 15:00 to 17:30. Eleven experienced QS investigators from ten
countries made presentations at this session.
Table of Contents of the Supplement
Foward J. Lippes School of Medicine Go to article (pdf)
Quinacrine sterilization: a retrospective J. Zipper,1 E. Kessel2 1Department of Obstetrics and Gynecology,
2Department of Public Health and
Preventive Medicine, Synopsis: A historical account of the development of this non-surgical female sterilization method
Quinacrine sterilization (QS): the ethical issues S. Bhattacharyya School of Social Science, Philosophy and Religion Synopsis: This paper examines various complex
ethical issues associated with quinacrine female sterilization (QS) and
presents a course of action that addresses many concerns from both sides.
25 years of quinacrine sterilization experience in Chile: review of 2,592 cases. J. Zipper1 , V. Trujillo2 1University of Chile, Sótero Del Río Hospital, Santiago, Chile 2San José Hospital, Santiago, Chile Synopsis: An assessment of research on quinacrine
sterilization (QS) from its inception in Chile through a quarter century of
safety and efficacy
Quinacrine nonsurgical female sterilization in Baroda, India: 23 years of follow-up of 84 women R.V. Bhatt Department of Obstetrics and Gynecology Synopsis: After 23 years following quinacrine
sterilization, no long term side effects were detectable in this series of 84
women. The failure rate was 3.7 per 100 women.
The rate of ectopic pregnancy for 24,589 quinacrine sterilization (QS) users compared to users of other methods and no method in 4 provinces in Vietnam, 1994-1996 D.T. Hieu,1&2 T.T. Luong2 1Director (retired) 2Department of Maternal and Child Health/
Family Planning Synopsis: Every ectopic pregnancy during 1994-1996
in four Vietnam provinces is identified. Ectopic rates for QS, surgical
sterilization, temporary methods and no contraceptive method are determined.
An FDA approved clinical trial of quinacrine sterilization (QS) J. Lippes, M. Brar, K. Gerbracht, P. Neff, S. Kokkinakis School of Medicine Synopsis: A clinical trial of QS was carried out on
ten patients with approval from the United States Food and Drug Administration.
Oviductal scars were identified with ultrasound in every patient.
A comparison of quinacrine sterilization (QS) and surgical sterilization (TL) in 600 women in Guizhou Province, China W. Lu,1 J. Zhu,2 C. Zhong,2 Y. Zhao2 1Center for Research on Population, 2Guizhou Provincial Research Institute
for Family Planning, Synopsis: Both methods were found to be safe. Among
women who received 2 insertions of quinacrine, the cumulative life-table
failure rate per 100 women at 24 months was 1.2 (SE=0.69) compared to 0.7 (SE=
0.47) among those surgically sterilized.
Quinacrine female nonsurgical sterilization (QS): endometrial assessment by vaginal ultrasonography in128 women C.R.C. Ferreira, D.R.B. Magalhães, D.C. Ferreira, M.Z. Hanan, A.F. Camargos Department of Obstetrics and Gynecology Synopsis: Transvaginal
ultrasound may be helpful for preventing clinical failures and to identify
blockage of the oviducts after QS.
The effect of special training for quinacrine sterilization (QS) in Faisalabad, Pakistan: a report on an 1833-women subset of 11,000 cases A. Bashir, M. Bashir, S. Afzal Mother & Child Welfare Association Synopsis: Outcomes of quinacrine sterilization
markedly improved after retraining of clinicians to use a newly accepted
transcervical insertion technique of 252 mg of quinacrine with efficacy of 1.1%
(SE 0.4) at 5 years of use.
Quinacrine sterilization (QS) among high-risk women: a study of 134 cases A.R. Sarin,1 R.K. Sarin2 1Department of Obstetrics &
Gynecology 2Aastha Medical Center Synopsis: 134 women at high risk for surgery
received quinacrine sterilization. After an average of 7.2 years of follow-up,
there have been no pregnancies or serious complications.
The acceptability, efficacy and safety of quinacrine non-surgical sterilization (QS), tubectomy and vasectomy in 5 provinces in the Red River Delta, Vietnam: a follow-up of 15,190 cases D.T. Hieu,1 T.T. Luong,2 P.T. Anh,2 D.H. Ngoc,2 L.Q. Duong2 1Director (retired) 1,2Department of Maternal and Child
Health/ Family Planning Synopsis: This is a retrospective study of 15,190
users of tubectomy, quinacrine sterilization and vasectomy who were sterilized
between 1989 and 1998 in 9 districts in 5 provinces of Vietnam. All are
interviewed.
A 22-year experience with quinacrine sterilization in a rural private clinic in Midnapore, India: a report on 5 protocols and 1838 cases A. Roy Family Practitioner Synopsis: Five different trials of QS were tried
sequentially. The currently recommended standard protocol is safe and shows
great promise with a failure rate of 0.8% at 3.5 years.
Quinacrine sterilization (QS) in Iran and the use of the HSG as a measure of success S. Soroodi-Moghaddam Private Family Planning Practice Synopsis: Twelve years of experience with quinacrine
sterilization in Tehran has found this method to be safe, effective and
acceptable. The use of HSG to determine success of quinacrine sterilization,
even under low pressure, results in a higher pregnancy rate.
Quinacrine sterilization of 1997 women in Daharpur, Midnapore, West Bengal, India: a comparison of 3 protocols S.K. Pal Family Practioner Synopsis: In a series of 1479 women using an age
dependent dose, no failures (pregnancies) have been reported after up to 8
years of follow-up. Two other protocols produced unacceptably high failure
rates.
Hysteroscopic and hysterosalpingographic study after intrauterine insertion of quinacrine pellets for non-surgical sterilization: results in 180 women S. El Sahwi, M. Kamel, M. El Faham, I. El Makhzangy Department of Obstetrics & Gynecology Synopsis: Study of QS occlusion by HSG and
hysteroscopy produced identical results. Two applications of quinacrine were
100% effective with minimal side effects.
Female sterilization with quinacrine using hysterosalpingography (HSG) as an endpoint after a single insertion protocol in Caracas, Venezuela A. Giugni Chalbaud, G. Plaza Mora Concepción Palacios Maternity Hospital Synopsis: After 30 patients underwent a single
insertion of 324 mg of quinacrine in Caracas, more than 86% of them had
bilateral tubal occlusion using HSG as an endpoint.
Quinacrine sterilization in Libya: 200 cases M.S. El Mahaishi, A.M. Azzidani Department of Gynecology & Obstetrics Synopsis: A study of quinacrine nonsurgical female
sterilization in 200 women in Libya found the method to be safe, effective and
acceptable.
Quinacrine sterilization (QS) in a private practice in Daytona
Beach, Florida: R.B. Whitney Medical Director Synopsis: This QS series, initiated in October 2000
in an American office setting, has produced results similar to those reported
by QS researchers worldwide.
Quinacrine sterilization (QS) experience in The Philippines: a preliminary report L.A. Alfonso, H.A. Albano Department of Obstetrics and Gynecology Synopsis: This is a preliminary report on a QS trial
in Cebu City, Philippines. Results of 36 women with 515 woman-months of use
are most encouraging.
Marie Stopes Society, Pakistan: 1000 cases of quinacrine sterilization (QS) Bilgrami M1, Shah L2 1Managing Director 2Technical Advisor Synopsis: 1000 QS cases were studied at 23 sites in
the outskirts of Karachi. After 4 years of follow-up, the crude pregnancy rate
was 2.0%. Side effects were minor.
8-Year follow-up in a randomized trial of one vs two transcervical insertions of quinacrine pellets for sterilization in Indonesia T. Agoestina Department of Obstetrics and Gynecology Synopsis: After 8 years, among 70 women receiving
one insertion, 14.3% became pregnant; there were no failures among 30 women
receiving 2 insertions. No long-term side effects or complications were
identified.
Quinacrine sterilization (QS) in Syria: a preliminary report on 297 cases V. Garabedian Private Practice Synopsis: From July 2001 to December 2002, 297 cases
of QS were performed. Four women experienced severe pain while other side
effects were mild. The one pregnancy was ectopic.
10-year follow-up of women who elected quinacrine sterilization (QS) in Wonosobo, Central Java, Indonesia A. Suhadi,1 M. Anwar,2 A. Soejoenoes3 1Department of Obstetrics and Gynecology,
2Department of Obstetrics and Gynecology,
3Department of Obstetrics and Gynecology,
Synopsis: In this QS study of 200 women, the 10-year
cumulative life table failure rate was 4.3 per 100 woman-years with a
continuation rate of 93%. No long-term complications or side effects were
identified.
Quinacrine sterilization (QS) in Costa Rica: 694 cases F. Alpizar Department of Obstetrics and Gynecology (retired) Synopsis: From 1989 until August 1993, 694 cases of
QS were performed in a private practice in Alajuela, Costa Rica. The gross
failure rate was 2.5%. Side effects were minor.
Quinacrine Sterilization (QS): Informed Consent Note to Readers: This questionnaire had more than 30 authors. It is the product of an initiative to create the best possible consent form for quinacrine sterilization (QS). From the beginning, the goal of the designers of this document has been to do our best to insure that women are so well informed about the procedure and its sequellae that they will be content with their decision whether or not to undergo QS. One contributor to developing this consent form was the late Dr. Michael Burnhill, Vice President for Medical Affairs, Planned Parenthood Federation of America. He played a key role in advancing the acceptance of QS in the United States and bringing this method to American women and consequently to women everywhere. This article is dedicated to Dr. Burnhill. Synopsis: A prototype consent form for quinacrine
sterilization has been developed and extensively evaluated. It is available
electronically and can be easily modified to fit local circumstances. |